policosanol cholesterol-10-1


Synonym: octacosanol (main component of policosanol).

Number of publications: more than 20

Molecule availability: over-the-counter

Route of administration: oral

Posology : from 10 to 20mg/day

!Please read the disclamer below!

Evidence of efficiency

Cholesterol:  Reduces the  LDL cholesterol level and increases HDL cholesterol, induces a reduction of blood pressure and a reduction of a heart attack risk in patients who present high levels of LDL [1].

Cardiovascular disease: LDL cholesterol is the first heart attack factor, its reduction thus has an important effect on lifespan.

Blood pressure: High levels of LDL cholestrol are one of the biggest causes of high blood pressure. A blood pressure too high can induce heart disorders, a kidney failure…

Supposed effects: Policosanol can reduce the levels of LDL cholesterol and increase those of HDL cholesterol, reduce blood pressure, support blood flow and reduce the risk of cardiovascular diseases.

Additional molecule: Rosuvastatin

Summary: Policosanol is a set of eight alcohols, the main one being octacosanol, which can be found in sugar cane. It can reduce LDL cholesterol production by the liver and increase levels of HDL cholesterol. Recent studies have shown that combining it with rosuvastatin allows for a more efficient reduction of cholesterol.[2]

Disclaimer :

Due to its possible antiplatelet effect, please refrain from taking policosanol before surgery.

In rare cases, policosanol can trigger polyuria (excessive production of urine), insomnia, headaches, dizziness, and light gastrointestinal disorders.

[1] “Policosanol as a New Inhibitor Candidate for Vascular Calcification in Diabetic Hyperlipidemic Rats,” n.d.

[2] Solomenchuk TM al et, “[EFFICIENCY OF CONCOMITANT USE OF POLICOSANOL AND ROSUVASTATIN IN PATIENTS WITH STABLE CORONARY ARTERY DISEASE AND MODERATE HEPATIC DYSFUNCTION]. – PubMed – NCBI,” accessed December 12, 2016, http://sci-hub.cc/https://www.ncbi.nlm.nih.gov/pubmed/27491147.


The information on the present website does not constitute either directly or indirectly any medical advice. The provided information is intended to inform and is in no way a substitute for the direct relationship between a patient and a health professional. Under no circumstances the information on the website are likely to make up for consulting, visiting and diagnosis by a licensed healthcare professional. Said information should not be interpreted as ensuring the promotion any some molecules or medical products.

Long Long Life will not be held liable for any action or decision-making in relation to the information on this website.

Long Long Life does not guarantee by any means any result following the implementation of the published information on the website herein.

Self-medication can be dangerous for your health, please seek medical advice before starting any treatment.

Hadrien Vielle



Hadrien is an engineer and was trained in biology, physics and bio-engineering at the École Polytechnique féminine in Paris.

More about the Long Long Life team

Hadrien est aujourd’hui ingénieur polyvalent après une formation en biologie, physique et bio-ingénierie à l’École Polytechnique féminine.

En savoir plus sur l’équipe de Long Long Life